What else causes low CD57?

[Todd36]

it seems like there are a lot of people with questions related to CD57.  It would be nice to have a doctor give an overview of the marker, eh?

anyway, i got my CD57 back today and I clocked in at 40 but I'm still waiting on western blot.  My dr said that it wasn't that low but it was lower than average.  The scientific literature says 60-360 is the normal range.  My white blood cell count is normal, EMG and NCS are normal, brain and C-spine MRI normal, and neurological exams are normal, but I'm still dealing with strange, diffuse pain and muscle twitching with the recent development of eye and throat pressure.

Besides lyme disease, what else does a low CD57 point to?  I know it can be low for HIV but that's out of the quesiton for me as I've been married for 10, and I had an HIV test before I was married and I haven't have blood transfusion.  SO...what else does a supressed CD57 indicate?  High CD57 is indicative of cancer, but low????

your input is appreciated.

Thanks,
Todd

[corky6969]

Hello Todd.
My name is elaine how are you todd?
Please can you send the CD57 ADD TO ME
***@****

I live in scotland, I have 4  past positive western blott tests for borrelia burgorferi in 2008 2009 2010. I got infected in 2006, i had the circulrar rash, flue lik,e illness. A gp asked if i saw a tick but did not treat me ,.i was gave wrong result by both gps and infectious disease Nhs concultant, They told me negative but results were positve,My mobility declinned over time I am now in a wheelchair at 48years old. When my positves were found by accident by a neurologist digging in my medical records. She caled to tell me.By this point id had it 4 years.THe infectios disease doctor,told me THERE IS NO WAY OF KNOWING IF LYMES CAUSED YOUR ILLNESS.AS THERE IS NO DIAGNOSTIC TEST. WHAT A JOKE.
He gave me trial 1 month antibiotics retested me. i was still [positove . i was sent packing. with NO DIAGNOSIS
I Have ran a coinfection test privetly and i show positive Anaplasma, l be running more.No Nhs doctor ran coinfection tests on me .
In the uk i can not get a doctor to give longterm antibiotics. I had a new test for lyme a immunoblott showed negative. But i have 4 past western blott.Iv read heard from ilads its because im in year 9 now im not giving a immune rersponce.
I need a uptodate lymes test but as all need antibodies iv got no chance. Ilads asked me why retest you have lymes disease you had the rash and positve bloods
Well i tried to get a diagnosis based on past positves, i was given POSTLYMES DISEASE SYNDROM. I need more treatment 1 month 4 years to late is not good enough. I am in bed more hours in day than up with a  exhausted spaced out zombie brain. Usual chronic muscle jpint pain,sensory pasasia. Muscle weakness in arms legs,irb , wonky heart rtyhm.host of other syptoms.
i will run CD57 AT ARMINLABS.COM.  HE is very nice german man always answers email questions. ilads receogmended him to me,, Realy the medical proffresion shoulkd develope a way of testing not relying on antibodies. Test that can see the disease in the microscope. to save the horrible merrygoround we lymes are all on, i am really fed up. I am soory if emails a mess hardly see with exhaustion. usual lighr sound heat is unbearable.  takr care

kind regards

elaine

[CraiginWales]

Do a full stealth pathogen panel if you can afford it with Armin. My latest showed Borrelia is still in remission , positive for Mycoplasma & Chlamydia Pneumoniae. I’m doing Buhner’s herbal protocol for both infections (12 months total) & only 5 weeks in I’m seeing really encouraging improvements. Don’t waste your time & energy with the NHS, been there, done that; got me nowhere. Find a sympathetic, understanding GP but remember they must stick to NICE guidelines. He’s been helpful in many other ways eg. When I did the Disulfiram protocol for Borrelia (group on FB), he did monthly liver function tests for non existent pain. Good luck

[JackieCalifornia]

Thanks for posting that quote.  I suspect there is a role for CD57 to play in diagnosis and perhaps tracking change (feeling better or feeling the same or feeling worse) as the patient progresses, but the earlier hopes some docs had that there is a strong and direct correlation between CD57 measurement on the one hand and the patient's immune reactions on the other hand seems to have faded somewhat.  ...  

The quote you post above suggests that CD57 may provide useful data, but is not the last word.  Let's all keep watch on developments and share them here.  Thanks again for the post --  

[GaPeachWoodstock]

I saw the following on the Igenex web site, so I thought that I would share it:  
"Therefore, for patients with a low CD57 count, Lyme disease and C.
pneumoniae infection should be included in differential diagnosis.
C. pneumoniae can cause acute respiratory disease, but it can also
persist in some patients with chronic respiratory conditions and
cardiovascular disease.

[JackieCalifornia]

Welcome to the Lyme page -- hope your treatment helps -- keep us posted!

[Seahorse0707]

Low CD57 and also be a sign of mold illness.  Please see survivingmold.com.  I am dealing with low CD57, high TGFB1 and C4a, and low MSH.  I also have high counts of mycoplasma and Epstein Barr counts.  My Dr. is treating me for mold.  I start the cholestyramine protocol tomorrow. Hope it works!  Been ill for 20 years.  

[SnapCracklePopkc]

Mine just came back at 8. It was 16 or 17 when I was sick, at 19 in December and plummettedto 8 after wisdom tooth extraction Im still functioning but running very very low.