What else causes low CD57?

[Todd36]

it seems like there are a lot of people with questions related to CD57.  It would be nice to have a doctor give an overview of the marker, eh?

anyway, i got my CD57 back today and I clocked in at 40 but I'm still waiting on western blot.  My dr said that it wasn't that low but it was lower than average.  The scientific literature says 60-360 is the normal range.  My white blood cell count is normal, EMG and NCS are normal, brain and C-spine MRI normal, and neurological exams are normal, but I'm still dealing with strange, diffuse pain and muscle twitching with the recent development of eye and throat pressure.

Besides lyme disease, what else does a low CD57 point to?  I know it can be low for HIV but that's out of the quesiton for me as I've been married for 10, and I had an HIV test before I was married and I haven't have blood transfusion.  SO...what else does a supressed CD57 indicate?  High CD57 is indicative of cancer, but low????

your input is appreciated.

Thanks,
Todd

[Floridagirl23]

Hi. I got sick about a year 1/2 ago after touring a farm. I finally found so someone to help me, but I'm confused by results. First, I tested positive for parvovirus, which makes sense because I had a rash indicative of parvovirus. Then, I only tested positive for band 23 on western blot and cd 57 of 36. All of the doctors wouldn't treat me because only band 23 wasn't enough proof of Lyme. I recently had another western blot and Elisa, all came back negative but cd57 is now 22. I also had my blood work sent to a Lyme specialist who said he checked my plasma and couldn't find anything.

Why would I test positive for band 23, which is Lyme specific, and now, nothing, all with a lowering cd57???

Any thoughts?

[cave76]

You asked why Dr. Jones doesn't use the CD57 test on children. I don't know because I never had to address that. You could email Dr. Jones and see if he can  tell you.

But the CD57 is not worth taking if you have to pay for it out of pocket. Even if your insurance pays for it----- that's up to you but as a test for disease progression or regression it's not reliable. As explained here and in other threads many times.

[Boosmommy]

Why not  for children?  My daughter had one.  Shes at 37.

[Boosmommy]

Hi I realize this is old but my daughter is 7 and may have Lyme disease.  So we also had a consult at Envita and will be going soon depending on cost.  Please share anything you can.  How is your husband??

[Lifeline01]

Check strep titers beta group A.  An autoimmune response to beta strep may cause low CD57.  Have you traveled out side the US rheumatic fever high in Caribbean and Europe, Asia , and Africa.  Have your doctor check at least two of the strep titers ASO and anti-DNase

[Ephedra]

I agree mojogal.  It matches the way I feel as well.  I think maybe perhaps it's a better indicator in some and maybe not so much for others.