Steady state levels should be reached before the 5th day at standard dosage (200mg twice a day.)
Pharmacokinetics
Absorption: Peak plasma levels of celecoxib occur
approximately 3 hrs after an oral dose. Under fasting
conditions, both peak plasma levels (Cmax) and area under the
curve (AUC) are roughly dose-proportional up to 200 mg BID;
at higher doses there are less than proportional increases in
Cmax and AUC [see Food Effects]. Absolute bioavailability
studies have not been conducted. With multiple dosing, steadystate
conditions are reached on or before Day 5.
Hi there,
You happened upon an MS forum. While not all of us are dx'd with MS, some of us have different dx's all together. And, some are seeking information and guidance, and experiences as it relates their current situation.
Like most folks, we have more than one thing going on at any given time. Lovemymonkeys, Jess is a regular forum member here and is seeking other peoples experiences with her post.
Hope this info helps,
~Shell
Sorry luv u need to seek an other persons help on this issue
Like Alex, I give meds a fair shake too unless experiencing reaction type side affects....I gave baclofen a couple months for side affects to subside relief. They did and it was very much worth the reduction in spasms.
Hope this kicks in for you soon!
-shell
I usually give a drug two weeks at least. As long as I am not having a dangerous side effect.