pharp inhibitors new wonder drug

[burrowes]

hello
my name is julie i have posted on this sight before, i would like to mention a new drug that has just come out of the phase 1 trials it is called OLAPARIB it has been all over the news today and in all the papers.
i have been on this drug for 2 years now and belive me i will never look back, it is designed for any cancers that are gene related the phase 2 trials are about to start so i suggest all of you who have a cancer that is genetic related try and get on it. oh by the way it is being trialed in the uk out of the royal marsden in surrey, the dr name is dr de bono, or Proff Stan Kay.
good luck
remember every one deserves a chance.

[Ramsay14]

My BRAC 1 & 2 testing was inconclusive as well.  "Genetic variant of uncertain significance."

[Teresa222]

I have decided to be BRCA tested very soon.  I guess many women have decided the same thing.  My sister had the BRCA test and it was "nonconclusive". Therefore, they want me to be tested and will do it FREE. Yes, free! Her doctor has agreed to coordinate the test if I will come see him. The problem is that he is in South GA. I am going anyway as soon as I can get there. I will drive down and plan a fun visit while I am there.

I wonder why it only works on BRCA positive women? We feel there is something going on in our family because my fraternal Grandmother had OVCA, my Mother has had breast cancer and my Father has prostrate cancer. My parents are 87 and 86 and have survived the BEAST's attacks on them to live a full, productive life.
Teresa

[bohan54]

They only work if you are BRCA 1 or 2.  Not sure where to get them yet.

[Trust_in_God]

Are there trials in the US now?  I want to try the PARP drug.

Dx 6/07 stage IV with metases to lliver & abdomen.  Surgery then 6 rounds Taxol/ Carboplatin.

Recurred 6-7 mos later. 2 mos in study maybe had antiangiogenesis drug.
2nd surgery 12/08.  3 more taxol/Cplatin...bad Rxn, so now finishing
8 x doxil. Still feel some tumors & lately, cramps.

So, PARP appears to be a better choice...
How to get into a trial here in US?
Some info said University of PA....