Can Remicade Cause Depression and Mood Swings

[cummings0309]

My husband takes Remicade for Crohn's Disease. He has severe mood swings after taking Remicade and then high and lows that resemble Depression. Are there any reported cases of this happening with anyone else?

[couldntbeworse]

I have been on Remicade now for 10 years for Crohn's Collitis and have been experiencing anxiety on occasion for a while now. I recently kept track as to when this was happening and it appears anywhere from a few hours to a week following my infusion treatment. It definitely is frustrating as I am usually easy going but the mood swings are taking their toll. I think they need to research this if they haven't already.

[TheLightSeeker]

Hi Renatho.
Look into the SCD program.
If it makes sense to you and you have the discipline to follow it,
it could help you get your life back.

Your mood swings along with weakness and "brain fog" are likely due to the imbalances caused by malabsorption and deficiencies, hallmark characteristics of UC.

Hope this helps.
Best wishes,
Niko

[Renatho]

Hello guys, my name is Renatho Azevedo, I'm from Brazil. I was diagnosed with Ulcerative Colitis in 2010, I took mesalazine and azatioprine, which worked at first but for not too long. The only thing that work for me and make me feel like have no colitis is corticosteroids, but the side effect for a long period doesn't worth. I have been taking remicade for almost a year and half now, I also have severe mood swings with highs and lows, sometimes i feel like i can't think straight. I feel weak, without motivation, no social life and all other stuffs that all of you commented here. This is so frustrating...

[tallen005]

My husband passed away just recently.  He was diagnosed with Crohn's Disease in 2002.  He was using Remicade for over 12 years and always said he would feel better after his infusion until after he had surgery about 1-1/2 years ago and then he became depressed, paranoid, anxious and had insomnia.  The last 2-3 weeks he would stay in bed most days only to come out and eat, drink or talk a few minutes.  He started missing work and would be up in the morning dressed and ready to go then not go.  Most of the time he was talking about stuff that didn't make any sense and mostly paranoid about everything.  He then ended up taking his life.  If you know what's best i would immediately stop taking  Remicade.  I would never have thought that this would happen because my husband never was suicidal?

[mrsmee]

I have been taking Remicade for almost a year now and I can soooooo relate to these stories. Shortly after my infusions I get overwhelmed with everyday stuff and have had anxiety attacks. My focus and concentration go out the window. I don't want to go anywhere or do the things I normally enjoy doing. It affects my daily life but seems to subside about a week before my next infusion. I have tried other biologics however they severely affected my short term memory. I know the Remicade has helped with some of the malabsorbtion and digestive issues but the way it seems to affect my state of mind and emotions really just frankly *****. I too am contimplating a different strategy to fighting this horrible and life changing disease.

[luckyruby]

my 16 year old son has been taking remicade for about 2 years. it seemed as though once in a while he would be in a funk and not want to do anything, we just ascribed it to being a teenager. But in the past year he has suffered from major depressive bouts where he won't leave his bed for days. none of this happened before remicade. after reading this forum we are taking him off remicade and will have to try something else.  Good Luck all