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What does "immunostain for e-cadherin is negative" mean?

mmf126
I have been diagnosed with "invasive Lobular Carcinoma"; "Immunostain for E-Cadherin is negative in the invasive tumor, supporting the diagnosis".
Can you pls explain?

Thanks!
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Avatar universal
mmf126
Thanks!
Regards!
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25201 tn?1255580836
japdip
E-Cadherin (protein) when found overexpressed (positive) is an indicator of a greater possibility of distant metastises of breast cancer. Any further explanation would be much too complicated to be understood completely.  Regards .....
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