After 16 week with Interferron + Simvastatin

[Otan]

Took 1st dose on 21 Oct 2011 and on 11 Jan 2012 HBV DNA not detected.  
Below is the lab history,                          

Date            13/9  20/10  21/10  11/11  16/11  9/12  15/12  6/1/12  11//1/12
                                   1st dose                                   12th dose
SGOT                    35*                          49*             63*                  67*
SGPT                    63*                          78*             89*                  90*
HBsAg     366.44  255.68                                                              176.4*
HBV DNA2.54x10^5                                                                   no detect

Result on week# 16

SGOT  86
SGPT  130
HBsAg  10.49

When HBsAg became zero, then what to do? Is that time to stimulate Anti-HBs?

[Otan]

OK, thanks for precious sugestions.
I have to be stronger about food.
And vaccine will be the fisrt thing to do.

[studyforhope]

This looks like an improvement. I hope you loose weight and eat extremely healthy to counteract fatty liver.
No need to check hbv dna at this time.
A vaccine could be used at this time to see if you can boost the antibody level, this will also help your Tcell response that is doing the major effort to keep you clear.
Avoid any major stress that could impair the precious immune control that you have now established.

[Otan]

I just back in my city Jakarta and made a blood check

6 Dec 2012;
AST -34
ALT -53
HBSAG - non reactive
Anti-HBS - reactive 71.43 mIU/mL
I am happy to find AST and ALT now close to normal not like before stay at high level, but my Anti-HBS tend to decline.
With this result, do I need to check HBV-DNA also or any other check should I do? Do I need to worry about Anti-HBS level going down?

Here are my previous lab results,
20/10/11 SGOT-35 SGPT-63;HBVDNA 2.54 10^5; HBSAG 255;
21/10/11 1st dose interferon
11/11/11 4th dose intrfrn
16/11/11 SGOT-49 SGPT-78
9/12/11  8th ds intrfrn
15/12/11 SGOT-63 SGPT-89
6/1/12  12th ds intrfrn
11/1/12 SGOT-67 SGPT-90 ;HBVDNA-undetect; HBSAG176;
3/2/12 16th ds intfrn
6/2/12  SGOT-86 SGPT-130 ; HBSAG-10.49;
10/2/12  17th ds intfrn
22/2/12  SGOT-139 SGPT-210
2/3/12  20th ds inter
7/3/12  SGOT-93 SGPT-161
9/3/12  SGOT-104 SGPT-171
12/3/12  SGOT-94 SGPT-166
30/3/12  24th ds
3/4/12  SGOT-93 SGPT-153
6/4/12 25th ds
10/4/12  SGOT-95 SGPT-143; HBSAG-0.08; HBSAB-negtv;
27/4/12  28th ds
2/5/12  SGOT-96 SGPT-150
6/7/12 38 ds
12/7/12S  GOT-93 SGPT-142; HBSAG- <0.05 iu/ml; HBSAB-negtv
17/7/12 Start taking Baraclude 0.5mg, 1 tablet per day
20/7/12 40th ds intrfn
25/7/12  GOT-108 SGPT-171
15/8/12  Last Baraclude taken
15/8/12  SGOT 117 SGPT 207; HbsAg- not reactive
24/8/12  HBSAB- 70 mIU/mL
14/9/12  48th dose intrfrn
19/9/12  SGOT-102 SGPT-162; HBV DNA- undetct; HBSAG quanty-
<0.05iu/ml; HBSAB- 122.58mIU/mL
16/10/12  SGOT-88 SGPT-165; HBSAB- 107.13 mIU/mL

[stef2011]

you may simply lose weight and see how alt changes, at bmi 21 you just get better health and improve liver function very much

as regards supplements easily available everywhere you may also try to increase hdl to higher than 60-80 by high dose omega 3, vit d3 and glutathione by injections or liposomal.

i d consider occult hbv only after excluding fatty liver, in any case occult hbv is of little importance as long as ast/alt normal, hbvdna very low and no hbsag mutants that increase hcc risk

[Otan]

Studyforhope,
At the moment I am in Perth Austrlia which is expensive for me to see doctor and lab.
Once I am back  in Jakarta I will do checkings.

[Jeff912000]

There is a lot of debate whether occult HBV occurs in individuals with antihbS.  By logic this is all protective antibody.